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Featured product
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Herbals
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Hypertension
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IND
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Insomnia
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JAPAN 2018
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JAPAN 2021
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JAPAN 2022
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Japan pipeline
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Lactams
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Macrolides
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Malaria
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Market info
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MONKEY POX
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Monoclonal antibody
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Nanotechnology
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NCE
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Neutraceuticals
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NEW USE DRUGS
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NICE
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NUCLEOTIDES
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obesity
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OCCULAR
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ocular hypertension
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osteoarthritis
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PAIN
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Parkinson's disease
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PATENT
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PATENTS
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Peptide drugs
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PFIZER
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PHASE 3
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PHASE1
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Phase2 drugs
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Phase3 drugs
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plaque psoriasis
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POLYMORPH
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Preclinical china
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Preclinical drugs
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Premture ejaculation
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Priority review
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PROCESS
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Promising clips
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Psoriasis
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QbD
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QIDP
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RADIOLABELLED
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Rare disease
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RARE PEDIATRIC DISEASE REVIEW
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Regenerative medicine
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Regulatory
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Resubmission FDA
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REVIEW
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rheumatoid arthritis
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SCHLEROSING AGENT
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Scottish Medicines Consortium
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Internal |
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sex arousal
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SFDA FAST TRACK
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SINGAPORE
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sNDA
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sNDA JAPAN
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Solid tumours
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Internal |
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spectroscopy
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Internal |
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SPOTLIGHT
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Internal |
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Stem cells
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Internal |
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SYNTHESIS
|
Internal |
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TIVE
|
Internal |
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TOXINS
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Internal |
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Translational medicine
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Internal |
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Transverse myletis
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Internal |
Passing Juice |
Tropical Disease Priority Review Voucher
|
Internal |
Passing Juice |
UK
|
Internal |
Passing Juice |
UNANI MEDICINE
|
Internal |
Passing Juice |
Uncategorized
|
Internal |
Passing Juice |
US HERBS
|
Internal |
Passing Juice |
USFDA SUBMISSION
|
Internal |
Passing Juice |
vaccine
|
Internal |
Passing Juice |
veterinary
|
Internal |
Passing Juice |
virus
|
Internal |
Passing Juice |
VITAMINS
|
Internal |
Passing Juice |
x ray contrast agent
|
Internal |
Passing Juice |
FACEBOOK
|
External |
Passing Juice |
Googleplus
|
External |
Passing Juice |
DR ANTHONY MELVIN CRASTO Ph.D
|
External |
Passing Juice |
ACT-132577, Aprocitentan
|
Internal |
Passing Juice |
Cefepime
|
Internal |
Passing Juice |
Berdazimer
|
Internal |
Passing Juice |
Tovorafenib
|
Internal |
Passing Juice |
Ceftobiprole
|
Internal |
Passing Juice |
DANICOPAN
|
Internal |
Passing Juice |
INAXAPLIN
|
Internal |
Passing Juice |
Golcadomide (CC-99282)
|
Internal |
Passing Juice |
Igermetostat
|
Internal |
Passing Juice |
Oditrasertib,
|
Internal |
Passing Juice |
Oditrasertib
|
Internal |
Passing Juice |
ORZILOBEN
|
Internal |
Passing Juice |
Opevesostat
|
Internal |
Passing Juice |
Sotuletinib HCl
|
Internal |
Passing Juice |
TACACICLIB, AUR-102, AURIGENE
|
Internal |
Passing Juice |
Capivasertib
|
Internal |
Passing Juice |
Eplontersen
|
Internal |
Passing Juice |
Iptacopan
|
Internal |
Passing Juice |
CAREBASTINE
|
Internal |
Passing Juice |
VODOBATINIB
|
Internal |
Passing Juice |
Etrasimod
|
Internal |
Passing Juice |
Motixafortide
|
Internal |
Passing Juice |
Evobrutinib
|
Internal |
Passing Juice |
Zuranolone
|
Internal |
Passing Juice |
EIDD-2173, ATI-2173, Fosclevudine alafenamide
|
Internal |
Passing Juice |
Palovarotene
|
Internal |
Passing Juice |
Zavegepant
|
Internal |
Passing Juice |
MAVORIXAFOR
|
Internal |
Passing Juice |
SMARTCHEM FROM ROW2 TECHNOLOGIES
|
Internal |
Passing Juice |
Amcenestrant (SAR 439859)
|
Internal |
Passing Juice |
Myself Anthony Crasto up for grabs as Advisor API & INT, Chem.
|
Internal |
Passing Juice |
‘Top 10 Prominent & Great Personalities of the year 2022’ campaign by Fame Finders. ANTHONY CRASTO
|
Internal |
Passing Juice |
SC-52458, FORASARTAN
|
Internal |
Passing Juice |
Adagrasib
|
Internal |
Passing Juice |
Nirsevimab
|
Internal |
Passing Juice |
Olutasidenib
|
Internal |
Passing Juice |
ABY 737
|
Internal |
Passing Juice |
Tolebrutinib, SAR 442168
|
Internal |
Passing Juice |
Mirvetuximab soravtansine-gynx
|
Internal |
Passing Juice |
TEREVALEFIM
|
Internal |
Passing Juice |
RELACORILANT
|
Internal |
Passing Juice |
Tremelimumab
|
Internal |
Passing Juice |
MILADEMETAN
|
Internal |
Passing Juice |
Daxibotulinumtoxin A
|
Internal |
Passing Juice |
Ozoralizumab
|
Internal |
Passing Juice |
Firibastat
|
Internal |
Passing Juice |
Futibatinib
|
Internal |
Passing Juice |
Lutetium (177Lu) chloride
|
Internal |
Passing Juice |
Enobosarm
|
Internal |
Passing Juice |
ELRAGLUSIB
|
Internal |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
N-Despropyl-macitentan
|
External |
Passing Juice |
WHO 10552
|
External |
Passing Juice |
Tryvio
|
External |
Passing Juice |
hypertension
|
External |
Passing Juice |
[1]
|
External |
Passing Juice |
Idorsia
|
External |
Passing Juice |
[2]
|
External |
Passing Juice |
by mouth
|
External |
Passing Juice |
endothelin-1
|
External |
Passing Juice |
endothelin A
|
External |
Passing Juice |
endothelin B
|
External |
Passing Juice |
[3]
|
External |
Passing Juice |
[4]
|
External |
Passing Juice |
[5]
|
External |
Passing Juice |
endothelin receptor antagonist
|
External |
Passing Juice |
Food and Drug Administration
|
External |
Passing Juice |
indicated
|
External |
Passing Juice |
hepatotoxicity
|
External |
Passing Juice |
edema
|
External |
Passing Juice |
anemia
|
External |
Passing Juice |
hemoglobin
|
External |
Passing Juice |
sperm count
|
External |
Passing Juice |
inflammation
|
External |
Passing Juice |
cell proliferation
|
External |
Passing Juice |
fibrosis
|
External |
Passing Juice |
vasoconstriction
|
External |
Passing Juice |
Janssen
|
External |
Passing Juice |
[6]
|
External |
Passing Juice |
Committee for Medicinal Products for Human Use
|
External |
Passing Juice |
European Medicines Agency
|
External |
Passing Juice |
[7]
|
External |
Passing Juice |
8324232
|
External |
Passing Juice |
TRYVIO
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US73589939&_cid=P12-LWDB8Y-85368-1
|
External |
noFollow |
-
|
External |
Passing Juice |
Trade names
|
External |
Passing Juice |
AHFS
|
External |
Passing Juice |
Drugs.com
|
External |
Passing Juice |
Tryvio
|
External |
Passing Juice |
Drug class
|
External |
Passing Juice |
Antihypertensive
|
External |
Passing Juice |
ATC code
|
External |
Passing Juice |
C02KN01
|
External |
Passing Juice |
WHO
|
External |
Passing Juice |
Legal status
|
External |
Passing Juice |
℞-only
|
External |
Passing Juice |
IUPAC name
|
External |
Passing Juice |
CAS Number
|
External |
Passing Juice |
1103522-45-7
|
External |
Passing Juice |
PubChem
|
External |
Passing Juice |
25099191
|
External |
Passing Juice |
IUPHAR/BPS
|
External |
Passing Juice |
10070
|
External |
Passing Juice |
DrugBank
|
External |
Passing Juice |
DB15059
|
External |
Passing Juice |
ChemSpider
|
External |
Passing Juice |
25027753
|
External |
Passing Juice |
UNII
|
External |
Passing Juice |
MZI81HV01P
|
External |
Passing Juice |
KEGG
|
External |
Passing Juice |
D11441
|
External |
Passing Juice |
ChEBI
|
External |
Passing Juice |
CHEBI:76609
|
External |
Passing Juice |
ChEMBL
|
External |
Passing Juice |
ChEMBL2165326
|
External |
Passing Juice |
Formula
|
External |
Passing Juice |
Molar mass
|
External |
Passing Juice |
JSmol
|
External |
Passing Juice |
Interactive image
|
External |
Passing Juice |
SMILES
|
External |
Passing Juice |
“Tryvio- aprocitentan tablet, film coated”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
“US FDA approves Idorsia’s once-daily Tryvio (aprocitentan) – the first and only endothelin receptor antagonist for the treatment of high blood pressure not adequately controlled in combination with other antihypertensives”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Current and Emerging Classes of Pharmacological Agents for the Management of Hypertension”
|
External |
Passing Juice |
doi
|
External |
Passing Juice |
10.1007/s40256-021-00510-9
|
External |
Passing Juice |
PMC
|
External |
Passing Juice |
PMID
|
External |
Passing Juice |
34878631
|
External |
Passing Juice |
10.1016/j.drudis.2023.103788
|
External |
Passing Juice |
37742911
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Novel Drug Approvals for 2024”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Idorsia reacquires aprocitentan rights from Janssen for $343m”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
“Jeraygo EPAR”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
10.1016/j.cpcardiol.2023.101686
|
External |
Passing Juice |
36893968
|
External |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
Cefepime hydrochloride
|
External |
Passing Juice |
I8X1O0607P
|
External |
Passing Juice |
Exblifep
|
External |
Passing Juice |
cephalosporin
|
External |
Passing Juice |
antibiotic
|
External |
Passing Juice |
Gram-positive
|
External |
Passing Juice |
Gram-negative
|
External |
Passing Juice |
bacteria
|
External |
Passing Juice |
meta-analysis
|
External |
Passing Juice |
mortality
|
External |
Passing Juice |
[1]
|
External |
Passing Juice |
[2]
|
External |
Passing Juice |
Bristol-Myers Squibb
|
External |
Passing Juice |
[3]
|
External |
Passing Juice |
generic drug
|
External |
Passing Juice |
citation needed
|
External |
Passing Juice |
[4]
|
External |
Passing Juice |
World Health Organization’s List of Essential Medicines
|
External |
Passing Juice |
[5]
|
External |
Passing Juice |
nosocomial
|
External |
Passing Juice |
pneumonia
|
External |
Passing Juice |
Pseudomonas aeruginosa
|
External |
Passing Juice |
empirical
|
External |
Passing Juice |
febrile
|
External |
Passing Juice |
neutropenia
|
External |
Passing Juice |
[6]
|
External |
Passing Juice |
Staphylococcus aureus
|
External |
Passing Juice |
Streptococcus pneumoniae
|
External |
Passing Juice |
Enterobacteriaceae
|
External |
Passing Juice |
plasmid
|
External |
Passing Juice |
chromosome
|
External |
Passing Juice |
beta-lactamases
|
External |
Passing Juice |
medical citation needed
|
External |
Passing Juice |
MIC
|
External |
Passing Juice |
[7]
|
External |
Passing Juice |
methoxy
|
External |
Passing Juice |
imino
|
External |
Passing Juice |
moiety
|
External |
Passing Juice |
β-lactamase
|
External |
Passing Juice |
methyl
|
External |
Passing Juice |
pyrrolidine
|
External |
Passing Juice |
-
|
External |
Passing Juice |
-
|
External |
Passing Juice |
/ˈsɛfɪpiːm/
|
External |
Passing Juice |
Monograph
|
External |
Passing Juice |
MedlinePlus
|
External |
Passing Juice |
a698021
|
External |
Passing Juice |
Intravenous
|
External |
Passing Juice |
intramuscular
|
External |
Passing Juice |
J01DE01
|
External |
Passing Juice |
WHO
|
External |
Passing Juice |
S4
|
External |
Passing Juice |
Pharmacokinetic
|
External |
Passing Juice |
Bioavailability
|
External |
Passing Juice |
IM
|
External |
Passing Juice |
Metabolism
|
External |
Passing Juice |
Hepatic
|
External |
Passing Juice |
Elimination half-life
|
External |
Passing Juice |
Excretion
|
External |
Passing Juice |
Renal
|
External |
Passing Juice |
88040-23-7
|
External |
Passing Juice |
5479537
|
External |
Passing Juice |
DB01413
|
External |
Passing Juice |
4586395
|
External |
Passing Juice |
807PW4VQE3
|
External |
Passing Juice |
D02376
|
External |
Passing Juice |
CHEBI:478164
|
External |
Passing Juice |
ChEMBL186
|
External |
Passing Juice |
CompTox Dashboard
|
External |
Passing Juice |
DTXSID70873208
|
External |
Passing Juice |
-
|
External |
Passing Juice |
ECHA InfoCard
|
External |
Passing Juice |
100.171.025
|
External |
Passing Juice |
-
|
External |
Passing Juice |
Interactive image
|
External |
Passing Juice |
Melting point
|
External |
Passing Juice |
InChI
|
External |
Passing Juice |
(verify)
|
External |
Passing Juice |
^
|
External |
Passing Juice |
10.1016/S1473-3099(07)70109-3
|
External |
Passing Juice |
17448937
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“FDA Alert: Cefepime (marketed as Maxipime)”
|
External |
Passing Juice |
the original
|
External |
Passing Juice |
^
|
External |
Passing Juice |
ISBN
|
External |
Passing Juice |
9783527607495
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
^
|
External |
Passing Juice |
World Health Organization
|
External |
Passing Juice |
hdl
|
External |
Passing Juice |
10665/325773
|
External |
Passing Juice |
^
|
External |
Passing Juice |
10.1007/bf03256641
|
External |
Passing Juice |
14720024
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Cefepime Susceptibility and Concentration Range (μg/ml) Minimum Inhibitory Concentration (MIC) Data”
|
External |
Passing Juice |
the original
|
External |
Passing Juice |
“Cefepime”
|
External |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
1846565-00-1
|
External |
Passing Juice |
Drug Trials Snapshot
|
External |
Passing Juice |
medication
|
External |
Passing Juice |
molluscum contagiosum
|
External |
Passing Juice |
[1]
|
External |
Passing Juice |
nitric oxide
|
External |
Passing Juice |
tetraethyl silicate
|
External |
Passing Juice |
[2]
|
External |
Passing Juice |
[3]
|
External |
Passing Juice |
[4]
|
External |
Passing Juice |
[5]
|
External |
Passing Juice |
topical
|
External |
Passing Juice |
international nonproprietary name
|
External |
Passing Juice |
[6]
|
External |
Passing Juice |
Berdazimer
|
External |
Passing Juice |
2
|
External |
Passing Juice |
3
|
External |
Passing Juice |
5
|
External |
Passing Juice |
“Zelsuvmi (berdazimer) topical gel”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“GSRS”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Drug Approval Package: Zelsuvmi”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“U.S. Food and Drug Administration Approves Zelsuvmi as a First-in-Class Medication for the Treatment of Molluscum Contagiosum”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
10665/330941
|
External |
Passing Juice |
10.1111/pde.15419
|
External |
Passing Juice |
37721050
|
External |
Passing Juice |
S2CID
|
External |
Passing Juice |
262045499
|
External |
Passing Juice |
10.36849/JDD.7230
|
External |
Passing Juice |
36745361
|
External |
Passing Juice |
256613906
|
External |
Passing Juice |
“New Developing Treatments for Molluscum Contagiosum”
|
External |
Passing Juice |
10.1007/s13555-022-00826-7
|
External |
Passing Juice |
36239905
|
External |
Passing Juice |
“The Antiviral Effect of Berdazimer Sodium on Molluscum Contagiosum Virus Using a Novel In Vitro Methodology”
|
External |
Passing Juice |
10.3390/v15122360
|
External |
Passing Juice |
38140601
|
External |
Passing Juice |
“Berdazimer Sodium (Code C174810)”
|
External |
Passing Juice |
NCT04535531
|
External |
Passing Juice |
ClinicalTrials.gov
|
External |
Passing Juice |
NCT03927703
|
External |
Passing Juice |
NCT03927716
|
External |
Passing Juice |
-
|
External |
Passing Juice |
DailyMed
|
External |
Passing Juice |
Berdazimer sodium
|
External |
Passing Juice |
Topical
|
External |
Passing Juice |
DBSALT003491
|
External |
Passing Juice |
DB18712
|
External |
Passing Juice |
ORT9SID4QY
|
External |
Passing Juice |
B23P7SM943
|
External |
Passing Juice |
D12758
|
External |
Passing Juice |
ChEMBL4298064
|
External |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
Ojemda
|
External |
Passing Juice |
glioma
|
External |
Passing Juice |
[1]
|
External |
Passing Juice |
[2]
|
External |
Passing Juice |
[3]
|
External |
Passing Juice |
[4]
|
External |
Passing Juice |
priority review
|
External |
Passing Juice |
breakthrough therapy
|
External |
Passing Juice |
orphan drug
|
External |
Passing Juice |
[5]
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US43216699&_cid=P22-LW02JF-43766-1
|
External |
noFollow |
-
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2009006389&_cid=P22-LW025M-38416-1
|
External |
noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US131345763&_cid=P22-LW02NH-45076-1
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US201396258&_cid=P22-LW02NH-45076-1
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=EP292571929&_cid=P22-LW02NH-45076-1
|
External |
noFollow |
“Archived copy”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
“FDA grants accelerated approval to tovorafenib for patients with relapsed or refractory BRAF-altered pediatric low-grade glioma”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
public domain
|
External |
Passing Juice |
^
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Day One’s Ojemda (tovorafenib) Receives US FDA Accelerated Approval for Relapsed or Refractory BRAF-altered Pediatric Low-Grade Glioma (pLGG), the Most Common Form of Childhood Brain Tumor”
|
External |
Passing Juice |
Archived
|
External |
Passing Juice |
^
|
External |
Passing Juice |
10665/363551
|
External |
Passing Juice |
“Tovorafenib”
|
External |
Passing Juice |
“Tovorafenib (Code C106254)”
|
External |
Passing Juice |
NCT04775485
|
External |
Passing Juice |
-
|
External |
Passing Juice |
Tovorafenib
|
External |
Passing Juice |
Antineoplastic
|
External |
Passing Juice |
1096708-71-2
|
External |
Passing Juice |
25161177
|
External |
Passing Juice |
DB15266
|
External |
Passing Juice |
28637796
|
External |
Passing Juice |
ZN90E4027M
|
External |
Passing Juice |
D12291
|
External |
Passing Juice |
CHEBI:167672
|
External |
Passing Juice |
ChEMBL3348923
|
External |
Passing Juice |
PDB ligand
|
External |
Passing Juice |
PDBe
|
External |
Passing Juice |
RCSB PDB
|
External |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
Ro-655788
|
External |
Passing Juice |
BAL-5788-001
|
External |
Passing Juice |
252188-71-9
|
External |
Passing Juice |
Press Release
|
External |
Passing Juice |
[5]
|
External |
Passing Juice |
cephalosporin antibacterial
|
External |
Passing Juice |
hospital-acquired pneumonia
|
External |
Passing Juice |
community-acquired pneumonia
|
External |
Passing Juice |
Basilea Pharmaceutica
|
External |
Passing Juice |
[6]
|
External |
Passing Juice |
[7]
|
External |
Passing Juice |
[8]
|
External |
Passing Juice |
[9]
|
External |
Passing Juice |
[10]
|
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[11]
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penicillin-binding protein 2a
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Enterococcus faecalis
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[12]
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[4]
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[13]
|
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Enterococcus faecium
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Haemophilus influenzae
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Escherichia coli
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Klebsiella pneumoniae
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Proteus mirabilis
|
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[14]
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[15]
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[16]
|
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Passing Juice |
[17]
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[18]
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Passing Juice |
[19]
|
External |
Passing Juice |
https://www.sciencedirect.com/topics/neuroscience/ceftobiprole
|
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noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2010136423&_cid=P20-LV0C7F-38615-1
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-
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[1]
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[2]
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International Drug Names
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Ceftobiprole
|
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Intravenous
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WHO
|
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[3]
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209467-52-7
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252188-71-9
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6918430
|
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DB04918
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23350302
|
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5T97333YZK
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D08885
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ChEMBL520642
|
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DTXSID40870229
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-
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100.129.666
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-
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Interactive image
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(what is this?)
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(verify)
|
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^
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“In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci”
|
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10.1128/AAC.45.3.825-836.2001
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11181368
|
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^
|
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“In vitro evaluation of BAL9141, a novel parenteral cephalosporin active against oxacillin-resistant staphylococci”
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12461013
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^
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“Prescription medicines: registration of new chemical entities in Australia, 2015”
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Archived
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https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/218275s000lbl.pdf
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^
|
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“Ceftobiprole medocaril in the treatment of hospital-acquired pneumonia”
|
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26573022
|
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^
|
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“Basilea announces distribution agreement with Cardiome to commercialize antibiotic Zevtera/Mabelio (ceftobiprole) in Europe and Israel”
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^
|
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“Basilea to launch Zevtera/Mabelio (ceftobiprole medocaril) in Europe through a commercial services provider”
|
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Archived
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^
|
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“Basilea announces launch of antibiotic Zevtera (ceftobiprole medocaril) in Germany”
|
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^
|
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“Swissmedic approves Basilea’s antibiotic Zevtera (ceftobiprole medocaril) for the treatment of pneumonia”
|
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^
|
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“Basilea signs exclusive distribution agreement for Zevtera (ceftobiprole medocaril) in the Middle East and North Africa with Hikma Pharmaceuticals LLC”
|
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^
|
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Passing Juice |
“Basilea announces that Health Canada approved Zevtera for the treatment of bacterial lung infections”
|
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Passing Juice |
^
|
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“Ceftobiprole medocaril: a review of its use in patients with hospital- or community-acquired pneumonia”
|
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25117196
|
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Passing Juice |
2925496
|
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Passing Juice |
^
|
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10.2165/00128071-200809040-00004
|
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18572975
|
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Passing Juice |
24357533
|
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Passing Juice |
^
|
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“Ceftobiprole activity against over 60,000 clinical bacterial pathogens isolated in Europe, Turkey, and Israel from 2005 to 2010”
|
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10.1128/AAC.02465-14
|
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24777091
|
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^
|
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10.1016/j.ijantimicag.2013.11.005
|
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24411474
|
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^
|
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10.1016/j.ijantimicag.2011.11.005
|
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22230331
|
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^
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“A phase 3 randomized double-blind comparison of ceftobiprole medocaril versus ceftazidime plus linezolid for the treatment of hospital-acquired pneumonia”
|
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10.1093/cid/ciu219
|
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24723282
|
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^
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“Zevtera 500 mg powder for concentrate for solution for infusion – Summary of Product Characteristics (SmPC)”
|
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^
|
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“Zeftera (previously Zevtera) EPAR”
|
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NCT03138733
|
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NCT03137173
|
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NCT00326287
|
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NCT03439124
|
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Ceftobiprole medocaril sodium salt
|
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Leave a comment
|
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Passing Juice |
1903768-17-1
|
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paroxysmal nocturnal hemoglobinuria
|
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[2]
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Passing Juice |
complement
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hemolysis
|
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complement C3
|
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[3]
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[4]
|
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Passing Juice |
1
|
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Passing Juice |
7
|
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eculizumab
|
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ravulizumab
|
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5
|
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3
|
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2
|
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6
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4
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https://patents.google.com/patent/US9796741
|
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noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023158772&_cid=P10-LUV2QK-25994-2
|
External |
noFollow |
https://patents.google.com/patent/US20230094124A1/en
|
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noFollow |
[5]
|
External |
Passing Juice |
[6]
|
External |
Passing Juice |
-
|
External |
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Complement factor D
|
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Passing Juice |
L04AJ09
|
External |
Passing Juice |
WHO
|
External |
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[1]
|
External |
Passing Juice |
DB15401
|
External |
Passing Juice |
75531295
|
External |
Passing Juice |
JM8C1SFX0U
|
External |
Passing Juice |
D11641
|
External |
Passing Juice |
ChEMBL4250860
|
External |
Passing Juice |
100.398.865
|
External |
Passing Juice |
-
|
External |
Passing Juice |
Interactive image
|
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^
|
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“Novel Drug Approvals for 2024”
|
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“Voydeya EPAR”
|
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Archived
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^
|
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“Voydeya (danicopan) granted first-ever regulatory approval in Japan for adults with PNH to be used in combination with C5 inhibitor therapy”
|
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Archived
|
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Passing Juice |
^
|
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^
|
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“First oral treatment against residual hemolytic anemia in patients with paroxysmal nocturnal hemoglobinuria”
|
External |
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^
|
External |
Passing Juice |
10665/330896
|
External |
Passing Juice |
10.1016/S2352-3026(23)00315-0
|
External |
Passing Juice |
38030318
|
External |
Passing Juice |
“Danicopan (Code C148181)”
|
External |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
apolipoprotein L1
|
External |
Passing Juice |
APOL1-mediated kidney disease
|
External |
Passing Juice |
[1]
|
External |
Passing Juice |
[2]
|
External |
Passing Juice |
US20230271945, Compound 2
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US406091252&_cid=P20-LR66PI-50127-1
|
External |
noFollow |
US20230271945, Compound 88
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US406091252&_cid=P20-LR66XU-55951-1
|
External |
noFollow |
US20230271945, Compound 89
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US406091252&_cid=P20-LR66ZZ-57878-1
|
External |
noFollow |
-
|
Internal |
Passing Juice |
RESEARCHGATE
|
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Passing Juice |
FACEBOOK
|
External |
Passing Juice |
-
|
External |
Passing Juice |
2446816-88-0
|
External |
Passing Juice |
147289591
|
External |
Passing Juice |
115009344
|
External |
Passing Juice |
S2SJ2RVZ6Y
|
External |
Passing Juice |
ChEMBL5083170
|
External |
Passing Juice |
Interactive image
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Inaxaplin for the treatment of APOL1-associated kidney disease”
|
External |
Passing Juice |
10.1038/s41581-023-00721-0
|
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Passing Juice |
37106136
|
External |
Passing Juice |
^
|
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Passing Juice |
10.1056/NEJMoa2202396
|
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Passing Juice |
36920755
|
External |
Passing Juice |
257534251
|
External |
Passing Juice |
Leave a comment
|
Internal |
Passing Juice |
WHO 12305
|
External |
Passing Juice |
https://www.sciencedirect.com/science/article/abs/pii/S0268960X22000686
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US376433363&_cid=P22-LR3AIE-86638-1
|
External |
noFollow |
-
|
External |
Passing Juice |
(MOL)
|
External |
Passing Juice |
(CDX)
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2022271557&_cid=P22-LR3A02-83684-1
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Leave a comment
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Internal |
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12655
|
External |
Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020020374&_cid=P22-LR1SQG-34075-1
|
External |
noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US415363922&_cid=P22-LR1S46-25135-1
|
External |
noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US338556625&_cid=P22-LR1S8P-27079-1
|
External |
noFollow |
-
|
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Passing Juice |
(MOL)
|
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Passing Juice |
(CDX)
|
External |
Passing Juice |
Peng, et al. Polysubstituted benzene compound and preparation method and use thereof.
|
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Passing Juice |
Leave a comment
|
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isobutyric
|
External |
Passing Juice |
ester
|
External |
Passing Juice |
prodrug
|
External |
Passing Juice |
GS-441524
|
External |
Passing Juice |
Gilead Sciences
|
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Phase III trials
|
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Passing Juice |
outpatient
|
External |
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COVID-19
|
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Passing Juice |
[1]
|
External |
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[2]
|
External |
Passing Juice |
oral bioavailability
|
External |
Passing Juice |
GS-443902
|
External |
Passing Juice |
adenylate kinase
|
External |
Passing Juice |
nucleotide diphosphate kinase
|
External |
Passing Juice |
[3]
|
External |
Passing Juice |
[4]
|
External |
Passing Juice |
ATP
|
External |
Passing Juice |
[5]
|
External |
Passing Juice |
[6]
|
External |
Passing Juice |
SARS-CoV-2
|
External |
Passing Juice |
[7]
|
External |
Passing Juice |
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00750
|
External |
noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=US410559063&_cid=P21-LQZ8TO-63689-1
|
External |
noFollow |
https://patentscope.wipo.int/search/en/detail.jsf?docId=CN390111903&_cid=P22-LR0ILC-38937-1
|
External |
noFollow |
-
|
External |
Passing Juice |
-
|
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Passing Juice |
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023167938&_cid=P22-LR0IC7-34984-1
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External |
noFollow |
-
|
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IUPAC name
|
External |
Passing Juice |
2647441-36-7
|
External |
Passing Juice |
Interactive image
|
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Passing Juice |
ChEMBL4863829
|
External |
Passing Juice |
115037299
|
External |
Passing Juice |
PubChem
|
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Passing Juice |
162513664
|
External |
Passing Juice |
Q55KCM7PXB
|
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Passing Juice |
standard state
|
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Passing Juice |
^
|
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Passing Juice |
“Clinical Trials Register”
|
External |
Passing Juice |
^
|
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Passing Juice |
“Gilead touts Veklury resilience against mutated coronavirus, plots phase 3 for new COVID oral antiviral”
|
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Passing Juice |
^
|
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Passing Juice |
“Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides”
|
External |
Passing Juice |
10.1016/j.bmcl.2012.02.105
|
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22446091
|
External |
Passing Juice |
^
|
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Passing Juice |
“Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment”
|
External |
Passing Juice |
10.1021/acsmedchemlett.0c00316
|
External |
Passing Juice |
32665809
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency”
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External |
Passing Juice |
10.1074/jbc.RA120.013679
|
External |
Passing Juice |
7242698
|
External |
Passing Juice |
32284326
|
External |
Passing Juice |
^
|
External |
Passing Juice |
“The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants”
|
External |
Passing Juice |
10.1126/scitranslmed.abm7621
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External |
Passing Juice |
35579533
|
External |
Passing Juice |
^
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External |
Passing Juice |
“Espacenet – search results”
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Infigratinib phosphate
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PALOVAROTENE | ORGAN…
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